Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 9/20 | 0.38 |
| ▸ | CTSS | P25774 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | APLNR | P35414 | 1/20 | 0.36 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22291895 | 0.84 | CA1 (0.41) | CA1CA2CA7MEN1GAA | |
| SCHEMBL21446918 | 0.82 | MEN1 (0.44) | CA1CA2CA7MEN1GAA | |
| SCHEMBL8251498 | 0.82 | CA1 (0.46) | CA1CA2CA7MEN1GAA | |
| SCHEMBL12634867 | 0.81 | CA1 (0.49) | CA1CA2CA7KMT2ACTSK | |
| SCHEMBL12634863 | 0.81 | CA1 (0.49) | CA1CA2CA7KMT2ACTSK | |
| SCHEMBL4117634 | 0.81 | CA1 (0.49) | CA1CA2CA7KMT2ACTSK | |
| SCHEMBL18646762 | 0.80 | MEN1 (0.39) | CA1CA2CA7MEN1GAA | |
| SCHEMBL21510947 | 0.79 | CA1 (0.47) | CA1CA2CA7MEN1GAA | |
| SCHEMBL27545964 | 0.79 | MEN1 (0.42) | CA1CA2CA7MEN1GAA | |
| SCHEMBL24938357 | 0.78 | MEN1 (0.41) | CA1CA2CA7MEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018081367-A1 | CYCLIC PEPTIDE TYROSINE TYROSINE COMPOUNDS AS MODULATORS OF NEUROPEPTIDE Y RECEPTORS | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-03 | — | — | WO | disclosed |