Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 7/20 | 0.85 |
| ▸ | GSTO1 | P78417 | 2/20 | 0.63 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | PDE4A | P27815 | 1/20 | 0.63 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.63 |
| ▸ | TTPA | P49638 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | AKT1 | P31749 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14393313 | 1.00 | PSEN1 (0.85) | PSEN1GSTO1PTPN1MEN1KMT2A | |
| SCHEMBL14335452 | 1.00 | PSEN1 (0.85) | PSEN1GSTO1PTPN1MEN1KMT2A | |
| SCHEMBL14393422 | 0.96 | PSEN1 (0.93) | PSEN1GSTO1PTPN1MEN1KMT2A | |
| SCHEMBL20107221 | 0.95 | PSEN1 (0.94) | PSEN1GSTO1PTPN1MEN1KMT2A | |
| .Alpha.-Tocopheryloxyacetic Acid SCHEMBL10074169 | 0.92 | PSEN1 (1.00) | PSEN1GSTO1PTPN1MEN1KMT2A | |
| SCHEMBL628461 | 0.92 | PSEN1 (1.00) | PSEN1GSTO1PTPN1MEN1KMT2A | |
| .Alpha.-Tocopheryloxyacetic Acid SCHEMBL2142535 | 0.92 | PSEN1 (1.00) | PSEN1GSTO1PTPN1MEN1KMT2A | |
| .Alpha.-Tocopheryloxyacetic Acid SCHEMBL2142528 | 0.92 | PSEN1 (1.00) | PSEN1GSTO1PTPN1MEN1KMT2A | |
| .Alpha.-Tocopheryloxyacetic Acid SCHEMBL20543237 | 0.91 | PSEN1 (0.98) | PSEN1GSTO1PTPN1MEN1KMT2A | |
| SCHEMBL13086409 | 0.88 | PSEN1 (0.70) | PSEN1GSTO1PTPN1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018081367-A1 | CYCLIC PEPTIDE TYROSINE TYROSINE COMPOUNDS AS MODULATORS OF NEUROPEPTIDE Y RECEPTORS | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-03 | — | — | WO | disclosed |