Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 2/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.38 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.38 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.38 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.38 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.37 |
| ▸ | TNF | P01375 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12302583 | 1.00 | PDPK1 (0.47) | PDPK1MTORSLC6A2SSTR1SSTR2 | |
| SCHEMBL14490098 | 1.00 | PDPK1 (0.47) | PDPK1MTORSLC6A2SSTR1SSTR2 | |
| SCHEMBL7163328 | 1.00 | PDPK1 (0.47) | PDPK1MTORSLC6A2SSTR1SSTR2 | |
| SCHEMBL6544929 | 1.00 | PDPK1 (0.47) | PDPK1MTORSLC6A2SSTR1SSTR2 | |
| SCHEMBL31065200 | 1.00 | PDPK1 (0.47) | PDPK1MTORSLC6A2SSTR1SSTR2 | |
| SCHEMBL25365555 | 1.00 | PDPK1 (0.47) | PDPK1MTORSLC6A2SSTR1SSTR2 | |
| SCHEMBL9051284 | 1.00 | PDPK1 (0.47) | PDPK1MTORSLC6A2SSTR1SSTR2 | |
| SCHEMBL16319220 | 1.00 | PDPK1 (0.47) | PDPK1MTORSLC6A2SSTR1SSTR2 | |
| SCHEMBL2456260 | 1.00 | PDPK1 (0.47) | PDPK1MTORSLC6A2SSTR1SSTR2 | |
| SCHEMBL15847976 | 0.98 | PDPK1 (0.45) | PDPK1MTORSLC6A2SSTR1SSTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107325070-B | Preparation method of 2,3, 4-tri-O-benzyl-6-deoxy-D-glucopyranose-1, 5-lactone | 吴赣药业（苏州）有限公司 | 2023-12-22 | — | — | CN | claimed |
| CN-107325070-B | Preparation method of 2,3, 4-tri-O-benzyl-6-deoxy-D-glucopyranose-1, 5-lactone | 吴赣药业（苏州）有限公司 | 2023-12-22 | — | — | CN | disclosed |
| CN-107325070-B | Preparation method of 2,3, 4-tri-O-benzyl-6-deoxy-D-glucopyranose-1, 5-lactone | 吴赣药业（苏州）有限公司 | 2023-12-22 | — | — | CN | disclosed |
| US-10550143-B2 | C,O-spiro aryl glycoside compounds, preparation therefor and use thereof | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2020-02-04 | — | — | US | disclosed |
| US-10550143-B2 | C,O-spiro aryl glycoside compounds, preparation therefor and use thereof | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2020-02-04 | — | — | US | disclosed |
| EP-3315502-A1 | C,O-SPIRO ARYL GLYCOSIDE COMPOUNDS, PREPARATION THEREFOR AND USE THEREOF | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2018-05-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10550143-B2 | C,O-spiro aryl glycoside compounds, preparation therefor and use thereof | SLC5A2, SLC5A1, GLP1R | PDPK1 1942/4885MTOR 1055/4885SLC6A2 585/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.