Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 20/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20108007 | 0.91 | DHODH (0.78) | DHODH | |
| SCHEMBL20107755 | 0.91 | DHODH (0.76) | DHODH | |
| SCHEMBL20108230 | 0.89 | DHODH (0.79) | DHODH | |
| SCHEMBL29815560 | 0.88 | DHODH (1.00) | DHODH | |
| SCHEMBL20107643 | 0.88 | DHODH (1.00) | DHODH | |
| SCHEMBL20107882 | 0.85 | DHODH (0.57) | DHODH | |
| SCHEMBL28953419 | 0.85 | DHODH (0.78) | DHODH | |
| SCHEMBL20107995 | 0.83 | DHODH (0.78) | DHODH | |
| SCHEMBL20108082 | 0.83 | DHODH (0.76) | DHODH | |
| SCHEMBL20108099 | 0.82 | DHODH (0.54) | DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3532468-B1 | 2,4,5-TRISUBSTITUTED 1,2,4-TRIAZOLONES USEFUL AS INHIBITORS OF DHODH | BAYER AG (DE) | 2022-03-23 | — | — | EP | disclosed |
| WO-2018077923-A1 | 2,4,5-TRISUBSTITUTED 1,2,4-TRIAZOLONES USEFUL AS INHIBITORS OF DHODH | BAYER AKTIENGESELLSCHAFT (DE) | 2018-05-03 | — | — | WO | disclosed |