Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 20/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24282504 | 0.92 | DHODH (0.78) | DHODH | |
| SCHEMBL20107775 | 0.89 | DHODH (0.70) | DHODH | |
| SCHEMBL20107748 | 0.88 | DHODH (0.86) | DHODH | |
| SCHEMBL20108017 | 0.83 | DHODH (0.78) | DHODH | |
| SCHEMBL20107735 | 0.83 | DHODH (0.78) | DHODH | |
| SCHEMBL20107594 | 0.82 | DHODH (0.79) | DHODH | |
| SCHEMBL20108033 | 0.82 | DHODH (0.78) | DHODH | |
| SCHEMBL20108251 | 0.82 | DHODH (0.78) | DHODH | |
| SCHEMBL21918082 | 0.81 | DHODH (0.79) | DHODH | |
| SCHEMBL21456815 | 0.80 | DHODH (0.52) | DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018077923-A1 | 2,4,5-TRISUBSTITUTED 1,2,4-TRIAZOLONES USEFUL AS INHIBITORS OF DHODH | BAYER AKTIENGESELLSCHAFT (DE) | 2018-05-03 | — | — | WO | disclosed |