Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21853522 | 0.91 | DHODH (0.53) | DHODH | |
| SCHEMBL20107874 | 0.88 | DHODH (0.48) | DHODH | |
| SCHEMBL20107880 | 0.87 | DHODH (0.62) | DHODH | |
| SCHEMBL20107862 | 0.86 | DHODH (0.51) | DHODH | |
| SCHEMBL29816233 | 0.86 | DHODH (0.51) | DHODH | |
| SCHEMBL20107613 | 0.82 | DHODH (0.53) | DHODH | |
| SCHEMBL21853461 | 0.80 | DHODH (0.71) | DHODH | |
| SCHEMBL21853460 | 0.80 | DHODH (0.71) | DHODH | |
| SCHEMBL24282435 | 0.79 | DHODH (0.54) | DHODH | |
| SCHEMBL28953501 | 0.77 | DHODH (0.56) | DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018077923-A1 | 2,4,5-TRISUBSTITUTED 1,2,4-TRIAZOLONES USEFUL AS INHIBITORS OF DHODH | BAYER AKTIENGESELLSCHAFT (DE) | 2018-05-03 | — | — | WO | disclosed |