Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 20/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20107649 | 0.82 | DHODH (0.59) | DHODH | |
| SCHEMBL20107969 | 0.81 | DHODH (0.77) | DHODH | |
| SCHEMBL24282508 | 0.79 | DHODH (0.77) | DHODH | |
| SCHEMBL20107819 | 0.78 | DHODH (0.78) | DHODH | |
| SCHEMBL20108282 | 0.78 | DHODH (0.79) | DHODH | |
| SCHEMBL20107783 | 0.77 | DHODH (0.67) | DHODH | |
| SCHEMBL20107720 | 0.77 | DHODH (0.79) | DHODH | |
| SCHEMBL20107741 | 0.71 | DHODH (1.00) | DHODH | |
| SCHEMBL20107739 | 0.71 | DHODH (1.00) | DHODH | |
| SCHEMBL29639564 | 0.71 | DHODH (1.00) | DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018077923-A1 | 2,4,5-TRISUBSTITUTED 1,2,4-TRIAZOLONES USEFUL AS INHIBITORS OF DHODH | BAYER AKTIENGESELLSCHAFT (DE) | 2018-05-03 | — | — | WO | disclosed |