SCHEMBL20108404

SCHEMBL20108404

CC(C)[C@@H]1NC(=O)N(CC(=O)N[C@@H](CS)C(=O)N[C@H](C)C(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N[C@H](Cc2ccccc2)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CS)C(N)=O)C1=O

nearest known ligand 0.59

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ MC4R P32245 8/20 0.59
▸ GRPR P30550 2/20 0.53
▸ GHSR Q92847 7/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20108329 0.95 MC4R (0.57) MC4RGRPRGHSR
SCHEMBL23430224 0.94 MC4R (0.59) MC4RGRPRGHSR
SCHEMBL20108414 0.94 MC4R (0.59) MC4RGRPRGHSR
SCHEMBL23430159 0.93 MC4R (0.58) MC4RGRPRGHSR
SCHEMBL20108498 0.92 MC4R (0.57) MC4RGRPRGHSR
SCHEMBL19334877 0.90 MC4R (0.55) MC4RGRPRGHSR
SCHEMBL20108277 0.90 MC4R (0.61) MC4RGRPRGHSR
SCHEMBL20108413 0.89 MC4R (0.59) MC4RGRPRGHSR
SCHEMBL20108311 0.89 MC4R (0.59) MC4RGRPRGHSR
SCHEMBL20108360 0.88 MC4R (0.53) MC4RGRPRGHSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210163536-A1 MELANOCORTIN RECEPTOR LIGANDS MODIFIED WITH HYDANTOIN IPSEN PHARMA SAS (FR) 2021-06-03 — — US disclosed
US-20180118784-A1 MELANOCORTIN RECEPTOR LIGANDS MODIFIED WITH HYDANTOIN IPSEN PHARMA S.A.S. (FR) 2018-05-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180118784-A1 MELANOCORTIN RECEPTOR LIGANDS MODIFIED WITH HYDANTOIN MC4R, MC3R, MC1R MC4R 1/4885GRPR 31/4885GHSR 103/4885
US-20210163536-A1 MELANOCORTIN RECEPTOR LIGANDS MODIFIED WITH HYDANTOIN MC4R, MC3R, MC1R MC4R 1/4885GRPR 31/4885GHSR 103/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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