⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17402840 | 0.92 | — | — | |
| SCHEMBL20108450 | 0.83 | — | — | |
| SCHEMBL17402836 | 0.81 | — | — | |
| SCHEMBL17394269 | 0.80 | — | — | |
| SCHEMBL17402843 | 0.80 | — | — | |
| SCHEMBL18755097 | 0.80 | JAK2 (0.62) | — | |
| SCHEMBL17394064 | 0.79 | — | — | |
| SCHEMBL20108399 | 0.79 | — | — | |
| SCHEMBL17393850 | 0.79 | — | — | |
| SCHEMBL16014984 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2964635-B1 | ANTIVIRAL COMPOUNDS | HOFFMANN LA ROCHE (CH) | 2018-05-02 | — | — | EP | disclosed |
| US-20160024107-A1 | THIENO[3,2-d]PYRIMIDINE, FURO[3,2-d]PYRIMIDINE, AND PYRROLO[3,2-D]PYRIMIDINES USEFUL FOR TREATING RESPIRATORY SYNCITIAL VIRUS INFECTIONS | GILEAD SCIENCES, INC. | 2016-01-28 | — | — | US | disclosed |