Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 15/20 | 0.78 |
| ▸ | SMO | Q99835 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20109654 | 0.85 | KDR (0.66) | KDRSMOKMT2A | |
| SCHEMBL20108806 | 0.81 | KMT2A (0.70) | KDRSMOKMT2AALDH1A1 | |
| SCHEMBL20108760 | 0.80 | SMO (0.70) | KDRSMOKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL20109683 | 0.80 | SMO (0.67) | KDRSMOKMT2A | |
| SCHEMBL20108794 | 0.80 | KMT2A (0.62) | KDRSMOKMT2AALDH1A1 | |
| SCHEMBL20109592 | 0.80 | KMT2A (0.65) | KDRSMOKMT2A | |
| SCHEMBL20108771 | 0.79 | SMO (0.66) | KDRSMOKMT2AALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL21221697 | 0.79 | SMO (0.69) | KDRSMOKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL21221837 | 0.79 | SMO (0.68) | KDRSMOKMT2AALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL21221743 | 0.79 | SMO (0.64) | KDRSMOKMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10947241-B2 | Phenyl phthalazine derivative, method for the preparation thereof, and pharmaceutical composition comprising the same | SEOUL NATIONAL UNIVERSITY HOSPITAL (KR) | 2021-03-16 | — | — | US | disclosed |
| US-20190241574-A1 | PHENYL PHTHALAZINE DERIVATIVE, METHOD FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | SEOUL NATIONAL UNIVERSITY HOSPITAL (KR) | 2019-08-08 | — | — | US | disclosed |
| WO-2018080216-A1 | PHENYL PHTHALAZINE DERIVATIVE, METHOD FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2018-05-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190241574-A1 | PHENYL PHTHALAZINE DERIVATIVE, METHOD FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | PAH, HDAC5, SLC5A1 | KDR 1710/4885SMO 767/4885KMT2A 804/4885 |
| US-10947241-B2 | Phenyl phthalazine derivative, method for the preparation thereof, and pharmaceutical composition comprising the same | PAH, HDAC5, SLC5A1 | KDR 1710/4885SMO 767/4885KMT2A 804/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.