Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.30 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20109923 | 0.86 | DPP8 (0.33) | HSD17B10DPP8DPP7 | |
| SCHEMBL24614018 | 0.79 | SMN1; SMN2 (0.44) | PTPN1SMN1; SMN2 | |
| SCHEMBL19999887 | 0.78 | — | — | |
| SCHEMBL19240731 | 0.77 | MEN1 (0.33) | — | |
| SCHEMBL17522138 | 0.75 | PIK3CD (0.43) | HSD17B10DPP8DPP7 | |
| SCHEMBL21651069 | 0.75 | PHGDH (0.37) | HSD17B10DPP8DPP7SMN1; SMN2 | |
| SCHEMBL17522199 | 0.75 | PIK3CD (0.43) | HSD17B10DPP8DPP7 | |
| SCHEMBL20937305 | 0.75 | KCNH2 (0.33) | — | |
| SCHEMBL17522201 | 0.75 | PIK3CD (0.43) | HSD17B10DPP8DPP7 | |
| SCHEMBL19421521 | 0.74 | MEN1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2534152-B1 | MACROCYCLES AS FACTOR XIA INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-05-02 | — | — | EP | disclosed |