Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2012218 | 0.98 | ALOX5AP (0.31) | ALOX5AP | |
| SCHEMBL1535854 | 0.93 | ALOX5AP (0.31) | ALOX5AP | |
| SCHEMBL8081901 | 0.87 | — | — | |
| SCHEMBL2008929 | 0.84 | — | — | |
| SCHEMBL2012975 | 0.81 | — | — | |
| SCHEMBL11755264 | 0.76 | — | — | |
| SCHEMBL18791833 | 0.76 | — | — | |
| SCHEMBL11760107 | 0.76 | HTR2A (0.31) | — | |
| Hydrochloric Acid SCHEMBL11761624 | 0.74 | HTR2A (0.30) | — | |
| SCHEMBL11197712 | 0.71 | SLC6A2 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11840495-B2 | Compositions and methods related to di-substituted bicyclo[2.2.1] heptanamine-containing compounds | THE BROAD INSTITUTE, INC. (US) | 2023-12-12 | — | — | US | disclosed |
| EP-4267549-A1 | COMPOSITIONS AND METHODS RELATED TO DI-SUBSTITUTED BICYCLO[2.2.1] HEPTANAMINE-CONTAINING COMPOUNDS | The Broad Institute Inc. (US) | 2023-11-01 | — | — | EP | disclosed |
| US-20220242815-A1 | COMPOSITIONS AND METHODS RELATED TO DI-SUBSTITUTED BICYCLO[2.2.1] HEPTANAMINE-CONTAINING COMPOUNDS | Instituto Carlos Slim de la Salud, A.C. (MX) | 2022-08-04 | — | — | US | disclosed |
| WO-2022140677-A1 | COMPOSITIONS AND METHODS RELATED TO DI-SUBSTITUTED BICYCLO[2.2.1] HEPTANAMINE-CONTAINING COMPOUNDS | THE BROAD INSTITUTE, INC. (US) | 2022-06-30 | — | — | WO | disclosed |
| EP-1672050-B1 | LUBRICATING OIL COMPOSITION | IDEMITSU KOSAN CO (JP) | 2015-12-09 | — | — | EP | disclosed |
| US-7964540-B2 | Lube base oil and lubricating oil composition | IDEMITSU KOSAN CO., LTD. (JP) | 2011-06-21 | — | — | US | disclosed |
| US-20070042915-A1 | Lube base oil and lubricating oil composition | IDEMITSU KOSAN CO., LTD. (JP) | 2007-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11840495-B2 | Compositions and methods related to di-substituted bicyclo[2.2.1] heptanamine-containing compounds | PHOSPHO1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, GRIN2C | ALOX5AP 3194/4885 |
| US-20220242815-A1 | COMPOSITIONS AND METHODS RELATED TO DI-SUBSTITUTED BICYCLO[2.2.1] HEPTANAMINE-CONTAINING COMPOUNDS | PHOSPHO1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, GRIN2C | ALOX5AP 3194/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.