Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 1/20 | 0.51 |
| ▸ | MDM2 | Q00987 | 4/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 7/20 | 0.38 |
| ▸ | CKS1B | P61024 | 1/20 | 0.36 |
| ▸ | SKP1 | P63208 | 1/20 | 0.36 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.35 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16304061 | 1.00 | PTGER4 (0.51) | PTGER4MDM2GSK3BRORCCKS1B | |
| SCHEMBL17684669 | 0.92 | PTGER4 (0.52) | PTGER4MDM2GSK3BRORCCKS1B | |
| SCHEMBL16305098 | 0.92 | PTGER4 (0.52) | PTGER4MDM2GSK3BRORCCKS1B | |
| SCHEMBL17684481 | 0.92 | PTGER4 (0.53) | PTGER4MDM2GSK3BRORCCKS1B | |
| SCHEMBL16304060 | 0.92 | PTGER4 (0.53) | PTGER4MDM2GSK3BRORCCKS1B | |
| SCHEMBL17684637 | 0.87 | PTGER4 (0.45) | PTGER4MDM2GSK3BRORCCKS1B | |
| SCHEMBL17684635 | 0.87 | PTGER4 (0.45) | PTGER4MDM2GSK3BRORCCKS1B | |
| SCHEMBL16305095 | 0.86 | PTGER4 (0.51) | PTGER4MDM2GSK3BRORCCKS1B | |
| SCHEMBL17684535 | 0.85 | PTGER4 (0.45) | PTGER4MDM2GSK3BRORCCKS1B | |
| SCHEMBL17684533 | 0.85 | PTGER4 (0.45) | PTGER4MDM2GSK3BRORCCKS1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3009426-B1 | 4-ALKYNYL IMIDAZOLE DERIVATIVE AND MEDICINE COMPRISING SAME AS ACTIVE INGREDIENT | KAKEN PHARMA CO LTD (JP) | 2018-05-02 | — | — | EP | disclosed |