SCHEMBL2011389

SCHEMBL2011389

[CH]1CCCCN1N1CCCCC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6838748 0.94
SCHEMBL3370457 0.92
SCHEMBL5526974 0.80 POLB (0.31)
SCHEMBL7238131 0.80
SCHEMBL7734499 0.79
SCHEMBL30601598 0.69
SCHEMBL9818279 0.69
SCHEMBL16717421 0.67
SCHEMBL4176778 0.65
SCHEMBL10395834 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103221397-A Novel compositions and methods for controlling nematode pests MONSANTO TECHNOLOGY LLC 2013-07-24 CN claimed
US-10858319-B2 Indole derivatives for use in medicine IOMET PHARMA LTD. (GB) 2020-12-08 US disclosed
US-20190084933-A1 INDOLE DERIVATIVES FOR USE IN MEDICINE IOMET PHARMA LTD. (GB) 2019-03-21 US disclosed
EP-3154953-A1 DUAL INHIBITOR COMPOUNDS FOR USE IN THE TREATMENT OF NEURODEGENERATIVE DISORDERS AND ALZHEIMER'S DISEASE Fondazione Istituto Italiano di Tecnologia (IT) 2017-04-19 EP disclosed
EP-3055293-A1 DIARYLALKYLAMINE REV-ERB ANTAGONISTS AND THEIR USE AS MEDICAMENTS Fondazione Istituto Italiano di Tecnologia (IT) 2016-08-17 EP disclosed
CN-105829296-A Azole compounds with imine-derived substituents 巴斯夫欧洲公司 2016-08-03 CN disclosed
CN-103221397-B Novel compositions and methods for controlling nematode pests MONSANTO TECHNOLOGY LLC (US) 2016-04-13 CN disclosed
WO-2015189830-A1 DUAL INHIBITOR COMPOUNDS FOR USE IN THE TREATMENT OF NEURODEGENERATIVE DISORDERS AND ALZHEIMER'S DISEASE FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) 2015-12-17 WO disclosed
WO-2015052283-A1 DIARYLALKYLAMINE REV-ERB ANTAGONISTS AND THEIR USE AS MEDICAMENTS FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) 2015-04-16 WO disclosed
CN-103221397-A Novel compositions and methods for controlling nematode pests MONSANTO TECHNOLOGY LLC 2013-07-24 CN disclosed
US-7115624-B1 Method of inhibiting protein tyrosine phosphatase 1B and/or T-cell protein tyrosine phosphatase 4 and/or other PTPases with an Asp residue at position 48 NOVO NORDISK A/S (DK) 2006-10-03 US disclosed
EP-1499747-A4 FORMATION AND USE OF SITE SPECIFIC NUCLEIC ACID COUPLED BINDING POLYPEPTIDES MOLECULAR SCIENCES INST (US) 2005-05-04 EP disclosed
EP-1499747-A2 FORMATION AND USE OF SITE SPECIFIC NUCLEIC ACID COUPLED BINDING POLYPEPTIDES The Molecular Sciences Institute (US) 2005-01-26 EP disclosed
WO-2003091404-A2 FORMATION AND USE OF SITE SPECIFIC NUCLEIC ACID COUPLED BINDING POLYPEPTIDES THE MOLECULAR SCIENCES INSTITUTE (US) 2003-11-06 WO disclosed
WO-2001010798-A1 SOLID PHASE SYNTHESIS OF OXA- AND THIAZOLES CHEMRX ADVANCED TECHNOLOGIES, INC. (US) 2001-02-15 WO disclosed
US-5952316-A FOR TREATING AUTOIMMUNE DISEASES, E.G., RHEUMATIOD ARTHRITIS YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1999-09-14 US disclosed
EP-0627406-B1 2-AMINO-1,3-PROPANEDIOL COMPOUND AND IMMUNOSUPPRESSANT YOSHITOMI PHARMACEUTICAL (JP) 1998-10-28 EP disclosed
US-5719176-A 2-amino-1,3-propanediol compound and immunosuppressant YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1998-02-17 US disclosed
US-5604229-A 2-amino-1,3-propanediol compound and immunosuppressant YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1997-02-18 US disclosed
EP-0627406-A1 2-AMINO-1,3-PROPANEDIOL COMPOUND AND IMMUNOSUPPRESSANT YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1994-12-07 EP disclosed