Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.55 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.55 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.55 |
| ▸ | PLG | P00747 | 2/20 | 0.55 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18891443 | 0.82 | PBRM1 (0.55) | F2PRSS1PRSS2PRSS3PLG | |
| SCHEMBL21589373 | 0.79 | PARP1 (0.53) | MEN1RAB9AKMT2ATDP1NPC1 | |
| SCHEMBL31650872 | 0.78 | F2 (0.55) | F2PRSS1PRSS2PRSS3PLG | |
| SCHEMBL8312824 | 0.78 | F2 (0.55) | F2PRSS1PRSS2PRSS3PLG | |
| SCHEMBL17730485 | 0.78 | F2 (0.55) | F2PRSS1PRSS2PRSS3PLG | |
| SCHEMBL2481256 | 0.78 | F2 (0.55) | F2PRSS1PRSS2PRSS3PLG | |
| SCHEMBL20114738 | 0.78 | F2 (0.55) | F2PRSS1PRSS2PRSS3PLG | |
| SCHEMBL13770411 | 0.77 | KMT2A (0.52) | F2PRSS1PRSS2PRSS3CYP3A4 | |
| SCHEMBL17354740 | 0.76 | F2 (0.53) | F2PRSS1PRSS2PRSS3PLG | |
| SCHEMBL12987444 | 0.73 | ASH1L (0.36) | F2PRSS1PRSS2PRSS3PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019040992-A1 | SYNTHETIC DERIVATIVES OF OLEOYL-LYSOPHOSPHATIDYLINOSITOL (OLEOLYL-LPI) AND USES THEREOF | CURTIN UNIVERSITY (AU) | 2019-03-07 | — | — | WO | disclosed |
| EP-2616450-B1 | SULFONAMIDE COMPOUNDS | KANCERA AB (SE) | 2018-05-02 | — | — | EP | disclosed |