SCHEMBL20114819

SCHEMBL20114819

c1ccc(-c2ccc(-c3nc(-c4ccccc4)nc(-n4c5ccccc5c5cc(-c6ccc7c(c6)Sc6ccccc6N7c6ccccc6)ccc54)n3)cc2)cc1

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HDAC6 Q9UBN7 1/20 0.33
PTGER4 P35408 1/20 0.32
KDM4E B2RXH2 1/20 0.31
ATM Q13315 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
TSPO P30536 1/20 0.31
BCHE P06276 2/20 0.31
ACHE P22303 1/20 0.31
NPY5R Q15761 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20114183 1.00 HDAC6 (0.33) HDAC6PTGER4KDM4EATML3MBTL1
SCHEMBL20114404 1.00 HDAC6 (0.33) HDAC6PTGER4KDM4EATML3MBTL1
SCHEMBL20114269 0.99 HDAC6 (0.33) HDAC6PTGER4KDM4EATML3MBTL1
SCHEMBL20114158 0.98 HDAC6 (0.35) HDAC6PTGER4TSPOBCHEACHE
SCHEMBL20114236 0.96 PTGER4 (0.32) PTGER4KDM4EATML3MBTL1TSPO
SCHEMBL17278458 0.93 KDM4E (0.38) HDAC6PTGER4KDM4EATML3MBTL1
SCHEMBL20114178 0.92 KDM4E (0.33) HDAC6PTGER4KDM4EATML3MBTL1
SCHEMBL20114152 0.91 HDAC6 (0.33) HDAC6PTGER4KDM4EATML3MBTL1
SCHEMBL20114050 0.91 KDM4E (0.33) HDAC6PTGER4KDM4EATML3MBTL1
SCHEMBL20114858 0.91 HDAC6 (0.32) HDAC6KDM4EATML3MBTL1BCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018080067-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE INCLUDING SAME 주식회사 두산 2018-05-03 WO disclosed