Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 18/20 | 0.40 |
| ▸ | SCN1A | P35498 | 17/20 | 0.40 |
| ▸ | SCN8A | Q9UQD0 | 17/20 | 0.40 |
| ▸ | SCN1B | Q07699 | 3/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25975292 | 0.84 | SCN1A (0.38) | SCN5ASCN1ASCN8A | |
| SCHEMBL19000632 | 0.84 | SCN9A (0.42) | SCN5ASCN1ASCN9ACYP3A4 | |
| SCHEMBL25973372 | 0.81 | SCN9A (0.43) | SCN5ASCN1ASCN9ACYP3A4 | |
| SCHEMBL19001187 | 0.80 | SCN9A (0.42) | SCN5ASCN1ASCN9ACYP3A4 | |
| SCHEMBL19000751 | 0.80 | SCN5A (0.42) | SCN5ASCN1ASCN9ACYP3A4 | |
| SCHEMBL20096055 | 0.80 | SCN5A (0.50) | SCN5ASCN1ASCN8ASCN9ACYP3A4 | |
| SCHEMBL20256507 | 0.79 | KDM4E (0.43) | SCN5ASCN1ASCN8ASCN9ACYP3A4 | |
| SCHEMBL20256595 | 0.79 | SCN9A (0.47) | SCN5ASCN1ASCN8ASCN1BSCN9A | |
| SCHEMBL20256133 | 0.79 | SCN5A (0.44) | SCN5ASCN1ASCN8ASCN1BSCN9A | |
| SCHEMBL20115559 | 0.79 | SCN5A (0.48) | SCN5ASCN1ASCN8ASCN9ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018081384-A1 | ACYL SULFONAMIDE NAV1.7 INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-05-03 | — | — | WO | disclosed |