Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 12/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 10/20 | 0.66 |
| ▸ | SCN9A | Q15858 | 10/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23913155 | 0.90 | SCN5A (0.54) | SCN5ACYP3A4SCN9A | |
| SCHEMBL20115622 | 0.90 | SCN5A (0.65) | SCN5ACYP3A4SCN9A | |
| SCHEMBL20115586 | 0.87 | SCN9A (0.67) | SCN5ACYP3A4SCN9A | |
| SCHEMBL23913156 | 0.85 | SCN9A (0.67) | SCN5ACYP3A4SCN9A | |
| SCHEMBL20115767 | 0.84 | SCN9A (0.68) | SCN5ACYP3A4SCN9A | |
| SCHEMBL20182507 | 0.83 | SCN9A (0.47) | SCN5ACYP3A4SCN9A | |
| SCHEMBL20115783 | 0.81 | SCN5A (0.64) | SCN5ACYP3A4SCN9A | |
| SCHEMBL19000751 | 0.81 | SCN5A (0.42) | SCN5ACYP3A4SCN9A | |
| SCHEMBL20115636 | 0.81 | SCN5A (0.65) | SCN5ACYP3A4SCN9A | |
| SCHEMBL20115642 | 0.81 | SCN9A (0.68) | SCN5ACYP3A4SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018081384-A1 | ACYL SULFONAMIDE NAV1.7 INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-05-03 | — | — | WO | disclosed |