Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | SMO | Q99835 | 3/20 | 0.49 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.46 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20676406 | 1.00 | TSHR (0.51) | TSHRHTTMEN1CYP3A4CYP2C9 | |
| SCHEMBL20117108 | 1.00 | TSHR (0.51) | TSHRHTTMEN1CYP3A4CYP2C9 | |
| SCHEMBL20116587 | 1.00 | TSHR (0.51) | TSHRHTTMEN1CYP3A4CYP2C9 | |
| SCHEMBL22357786 | 0.88 | HTT (0.50) | TSHRHTTMEN1CYP3A4CYP2C9 | |
| SCHEMBL21609973 | 0.83 | SMO (0.55) | TSHRHTTMEN1CYP3A4CYP2C9 | |
| SCHEMBL20660679 | 0.83 | SMO (0.49) | TSHRHTTMEN1CYP3A4CYP2C9 | |
| SCHEMBL22357969 | 0.82 | HTT (0.55) | TSHRHTTMEN1CYP3A4CYP2C9 | |
| SCHEMBL22357775 | 0.82 | SMO (0.55) | TSHRHTTMEN1CYP3A4CYP2C9 | |
| SCHEMBL20116297 | 0.81 | EPHX2 (0.69) | TSHRHTTMEN1CYP3A4CYP2C9 | |
| SCHEMBL22358183 | 0.81 | HTT (0.56) | TSHRHTTMEN1CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018081167-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS (US) | 2018-05-03 | — | — | WO | disclosed |