Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 11/20 | 0.39 |
| ▸ | SMO | Q99835 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20676644 | 0.83 | GRM5 (0.42) | GRM5SMOALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL20116709 | 0.83 | GRM5 (0.42) | GRM5SMOALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL20116719 | 0.83 | GRM5 (0.42) | GRM5SMOALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL20676702 | 0.78 | GRM5 (0.42) | GRM5ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL20116359 | 0.78 | GRM5 (0.42) | GRM5ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL20116351 | 0.78 | GRM5 (0.42) | GRM5ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL22357845 | 0.78 | GRM5 (0.42) | GRM5 | |
| SCHEMBL22358358 | 0.78 | GRM5 (0.46) | GRM5SMOALDH1A1 | |
| SCHEMBL22357853 | 0.78 | GRM5 (0.42) | GRM5 | |
| SCHEMBL22358113 | 0.78 | GRM5 (0.42) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018081167-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS (US) | 2018-05-03 | — | — | WO | disclosed |