Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 5/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12723078 | 1.00 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3HTR6OPRM1 | |
| SCHEMBL20941801 | 0.88 | MAPK1 (0.45) | SLC6A2SLC6A4SLC6A3HTR6MAPK1 | |
| SCHEMBL24364555 | 0.77 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3HTR6OPRM1 | |
| SCHEMBL25152671 | 0.77 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3HTR6OPRM1 | |
| SCHEMBL14818545 | 0.77 | — | — | |
| SCHEMBL25492728 | 0.75 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3HTR6OPRM1 | |
| SCHEMBL19174820 | 0.75 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3HTR6OPRM1 | |
| SCHEMBL19398853 | 0.74 | SLC6A2 (0.44) | SLC6A2SLC6A4SLC6A3HTR6OPRM1 | |
| SCHEMBL19841838 | 0.74 | SLC6A2 (0.44) | SLC6A2SLC6A4SLC6A3HTR6OPRM1 | |
| SCHEMBL13649123 | 0.74 | SLC6A2 (0.44) | SLC6A2SLC6A4SLC6A3HTR6OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081812-A2 | AKT3 MODULATORS | GEORGIAMUNE LLC (US) | 2023-05-11 | — | — | WO | disclosed |
| EP-2964639-B1 | PYRIMIDINE CARBOXAMIDES AS SODIUM CHANNEL BLOCKERS | PURDUE PHARMA LP (US) | 2018-05-02 | — | — | EP | disclosed |