Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 4/20 | 0.33 |
| ▸ | HTR2C | P28335 | 5/20 | 0.33 |
| ▸ | HTR2B | P41595 | 4/20 | 0.33 |
| ▸ | HTR2A | P28223 | 3/20 | 0.33 |
| ▸ | BRD4 | O60885 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20117614 | 0.89 | FGFR2 (0.32) | GRM2HTR2CHTR2BHTR2A | |
| SCHEMBL20111311 | 0.89 | HTR2A (0.34) | GRM2HTR2CHTR2BHTR2A | |
| SCHEMBL20111705 | 0.86 | HTR2A (0.30) | HTR2CHTR2BHTR2A | |
| SCHEMBL20111361 | 0.86 | HPGD (0.36) | HTR2CHTR2BHTR2ABRD4PDE10A | |
| SCHEMBL20117898 | 0.84 | HPGD (0.39) | BRD4SLC6A4HTR6 | |
| SCHEMBL20102524 | 0.83 | EPHX1 (0.32) | ALDH1A1SLC6A4 | |
| SCHEMBL20117897 | 0.83 | KCNH2 (0.33) | ALDH1A1GLA | |
| SCHEMBL20102519 | 0.81 | HTR2A (0.34) | HTR2CHTR2BHTR2ABRD4PDE10A | |
| SCHEMBL20117603 | 0.80 | — | — | |
| SCHEMBL20102590 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3315583-A1 | LIQUID CRYSTAL COMPOUND HAVING BIPHENYLENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC Corporation (JP) | 2018-05-02 | — | — | EP | disclosed |