SCHEMBL20117747

SCHEMBL20117747

CC1CCC(COc2cc3c(c(F)c2F)-c2c-3ccc(OCC3CCC(C4CCC(C)CC4)CC3)c2F)CC1

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.36
SCN9A Q15858 6/20 0.35
HTR2A P28223 2/20 0.34
HTR2C P28335 2/20 0.34
HTR2B P41595 2/20 0.34
FFAR1 O14842 1/20 0.33
BRD4 O60885 2/20 0.33
PDE4A P27815 1/20 0.32
PDE4B Q07343 1/20 0.32
PDE4C Q08493 1/20 0.32
PDE4D Q08499 1/20 0.32
SLC6A4 P31645 1/20 0.32
HTR6 P50406 1/20 0.32
KCNT1 Q5JUK3 1/20 0.32
RIPK1 Q13546 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20111270 0.93 HPGD (0.36) HPGDSCN9AHTR2AHTR2CHTR2B
SCHEMBL20111285 0.93 HPGD (0.36) HPGDSCN9AHTR2AHTR2CHTR2B
SCHEMBL20111312 0.92 HPGD (0.34) HPGDSCN9AHTR2AHTR2CHTR2B
SCHEMBL20117630 0.92 HPGD (0.34) HPGDSCN9AHTR2AHTR2CHTR2B
SCHEMBL20111716 0.90 SCN9A (0.36) HPGDSCN9AHTR2AHTR2CHTR2B
SCHEMBL20117676 0.89 HPGD (0.34) HPGDSCN9AHTR2AHTR2CHTR2B
SCHEMBL20117803 0.89 SCN9A (0.35) HPGDSCN9AHTR2AHTR2CHTR2B
SCHEMBL20111715 0.88 HPGD (0.35) HPGDSCN9AHTR2AHTR2CHTR2B
SCHEMBL20111242 0.87 HPGD (0.33) HPGDSCN9AHTR2AHTR2CHTR2B
SCHEMBL20111361 0.86 HPGD (0.36) HPGDSCN9AHTR2AHTR2CHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3315583-A1 LIQUID CRYSTAL COMPOUND HAVING BIPHENYLENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC Corporation (JP) 2018-05-02 EP disclosed