Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20117765 | 0.90 | HSP90AA1 (0.54) | HSP90AA1HSP90B1 | |
| SCHEMBL20117932 | 0.90 | HSP90B1 (0.52) | HSP90AA1HSP90B1 | |
| SCHEMBL20117820 | 0.85 | HSP90B1 (0.52) | HSP90AA1HSP90B1 | |
| SCHEMBL20117966 | 0.84 | HSP90AA1 (0.49) | HSP90AA1HSP90B1 | |
| SCHEMBL20117962 | 0.84 | HSP90AA1 (0.51) | HSP90AA1HSP90B1 | |
| SCHEMBL20117826 | 0.83 | HSP90AA1 (0.54) | HSP90AA1HSP90B1 | |
| SCHEMBL20117960 | 0.83 | HSP90B1 (0.64) | HSP90AA1HSP90B1 | |
| SCHEMBL20117933 | 0.82 | HSP90B1 (0.51) | HSP90AA1HSP90B1 | |
| SCHEMBL20117967 | 0.82 | HSP90B1 (0.51) | HSP90AA1HSP90B1 | |
| SCHEMBL24217586 | 0.81 | HSP90AA1 (0.63) | HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220024869-A1 | GRP94 SELECTIVE INHIBITORS AND USES THEREOF | UNIVERSITY OF KANSAS | 2022-01-27 | — | — | US | disclosed |
| WO-2018081814-A1 | GRP94 SELECTIVE INHIBITORS AND USES THEREOF | UNIVERSITY OF KANSAS (US) | 2018-05-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220024869-A1 | GRP94 SELECTIVE INHIBITORS AND USES THEREOF | GRPR, HSP90B1, HSPE1 | HSP90AA1 9/4885HSP90B1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.