Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | F2 | P00734 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | KCNH3 | Q9ULD8 | 3/20 | 0.48 |
| ▸ | IDH1 | O75874 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29368367 | 1.00 | GAA (0.61) | GAATDP1HTTMAPK1LMNA | |
| SCHEMBL15131652 | 0.91 | GAA (0.52) | GAATDP1HTTMAPK1LMNA | |
| SCHEMBL2684956 | 0.89 | GAA (0.83) | GAATDP1HTTMAPK1LMNA | |
| SCHEMBL8041736 | 0.88 | GAA (0.74) | GAATDP1HTTMAPK1LMNA | |
| SCHEMBL2682570 | 0.85 | KMT2A (0.53) | GAATDP1HTTMAPK1LMNA | |
| SCHEMBL29435432 | 0.85 | MAPK1 (0.50) | GAATDP1HTTMAPK1LMNA | |
| SCHEMBL28674495 | 0.85 | GAA (0.58) | GAATDP1HTTMAPK1LMNA | |
| SCHEMBL29462964 | 0.85 | KMT2A (0.53) | GAATDP1HTTMAPK1LMNA | |
| SCHEMBL8827500 | 0.85 | MAPK1 (0.50) | GAATDP1HTTMAPK1LMNA | |
| SCHEMBL66639 | 0.85 | MAPK1 (0.50) | GAATDP1HTTMAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11746126-B2 | Bicyclic peptide ligands with detectable moieties and uses thereof | Bicyclerd Limited (GB) | 2023-09-05 | — | — | US | disclosed |
| US-20210079045-A1 | BICYCLIC PEPTIDE LIGANDS WITH DETECTABLE MOIETIES AND USES THEREOF | Bicyclerd Limited (GB) | 2021-03-18 | — | — | US | disclosed |
| US-10444626-B2 | Hologram recording composition, hologram recording medium, and method of producing hologram recording medium | SONY CORPORATION (JP) | 2019-10-15 | — | — | US | disclosed |
| US-20180120694-A1 | HOLOGRAM RECORDING COMPOSITION, HOLOGRAM RECORDING MEDIUM, AND METHOD OF PRODUCING HOLOGRAM RECORDING MEDIUM | SONY CORPORATION (JP) | 2018-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11746126-B2 | Bicyclic peptide ligands with detectable moieties and uses thereof | VIP, NGLY1, GRPR | GAA 3314/4885TDP1 4302/4885HTT 2023/4885 |
| US-20210079045-A1 | BICYCLIC PEPTIDE LIGANDS WITH DETECTABLE MOIETIES AND USES THEREOF | VIP, NGLY1, GRPR | GAA 3314/4885TDP1 4302/4885HTT 2023/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.