SCHEMBL20118150

SCHEMBL20118150

CCCc1ccc(-c2ccc(-c3cc(F)c(C(F)(F)Oc4cc(F)c(OC(F)(F)F)c(F)c4)c(F)c3)c(F)c2)cc1

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GRM2 Q14416 1/20 0.36
ALOX5AP P20292 1/20 0.34
FEN1 P39748 1/20 0.34
S1PR1 P21453 2/20 0.34
S1PR3 Q99500 2/20 0.34
RARB P10826 3/20 0.33
RARA P10276 1/20 0.33
RARG P13631 1/20 0.33
FFAR1 O14842 1/20 0.31
FFAR4 Q5NUL3 1/20 0.31
MAOB P27338 2/20 0.31
MCL1 Q07820 1/20 0.30
SLC13A5 Q86YT5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12625584 0.93 RARB (0.43) GRM2ALOX5APFEN1S1PR1S1PR3
SCHEMBL15744608 0.92 RARB (0.33) GRM2RARBRARARARGFFAR4
SCHEMBL12625575 0.92 RARB (0.42) GRM2ALOX5APFEN1S1PR1S1PR3
SCHEMBL20118273 0.91 GRM2 (0.39) GRM2ALOX5APFEN1FFAR1FFAR4
SCHEMBL15744321 0.91 GRM2 (0.35) GRM2ALOX5APFEN1S1PR1S1PR3
SCHEMBL15745124 0.91 GRM2 (0.35) GRM2ALOX5APFEN1S1PR1S1PR3
SCHEMBL12205482 0.90 GRM2 (0.39) GRM2ALOX5APFEN1S1PR1S1PR3
SCHEMBL12625465 0.90 S1PR1 (0.35) GRM2ALOX5APFEN1S1PR1S1PR3
SCHEMBL2395062 0.90 S1PR1 (0.35) GRM2ALOX5APFEN1S1PR1S1PR3
SCHEMBL30106832 0.90 S1PR1 (0.35) GRM2ALOX5APFEN1S1PR1S1PR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180119011-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE THEREOF JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2018-05-03 US disclosed