Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13978020 | 0.83 | TP53 (0.44) | NPC1PKMRAB9AKDM4EGLA | |
| SCHEMBL23869661 | 0.78 | CYP1A2 (0.42) | NPC1PKMRAB9AKDM4EGLA | |
| SCHEMBL13729056 | 0.74 | CYP2D6 (0.41) | KDM4ECYP1A2NISCHCYP2D6CYP19A1 | |
| SCHEMBL17716526 | 0.73 | TP53 (0.69) | NPC1PKMRAB9AKDM4EGLA | |
| SCHEMBL19543317 | 0.73 | CYP2D6 (0.40) | NPC1PKMRAB9AKDM4EGLA | |
| SCHEMBL17664870 | 0.72 | TP53 (0.36) | CYP2D6CYP2C9TP53HTTHSP90AA1 | |
| SCHEMBL28221285 | 0.71 | NISCH (0.38) | NPC1PKMRAB9AKDM4EGLA | |
| SCHEMBL4780009 | 0.69 | NPC1 (0.46) | NPC1PKMRAB9AKDM4EGLA | |
| SCHEMBL9963181 | 0.69 | HTT (0.61) | NPC1PKMRAB9AKDM4EGLA | |
| SCHEMBL17662363 | 0.69 | TP53 (0.34) | TP53HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3315531-A1 | 8-ARM POLYETHYLENE GLYCOL DERIVATIVE, MANUFACTURING METHOD AND MODIFIED BIO-RELATED SUBSTANCE THEREBY | Xiamen Sinopeg Biotech Co., Ltd. (CN) | 2018-05-02 | — | — | EP | disclosed |