Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 15/20 | 0.63 |
| ▸ | MKNK1 | Q9BUB5 | 5/20 | 0.51 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9902335 | 0.82 | FYN (0.46) | FYNMKNK1AAK1 | |
| SCHEMBL9902267 | 0.82 | DYRK1A (0.58) | FYNMKNK1AAK1 | |
| SCHEMBL16010419 | 0.82 | FYN (0.70) | FYNMKNK1 | |
| SCHEMBL15389466 | 0.80 | AAK1 (0.45) | FYNMKNK1AAK1 | |
| SCHEMBL9902738 | 0.80 | AAK1 (0.45) | FYNMKNK1AAK1 | |
| SCHEMBL9902863 | 0.78 | DYRK3 (0.42) | FYNMKNK1AAK1 | |
| SCHEMBL9903277 | 0.78 | DYRK3 (0.42) | FYNMKNK1AAK1 | |
| SCHEMBL15255029 | 0.78 | FYN (0.46) | FYNMKNK1AAK1 | |
| SCHEMBL16009938 | 0.78 | FYN (1.00) | FYNMKNK1 | |
| SCHEMBL20119736 | 0.78 | FYN (0.61) | FYNMKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2822559-B1 | IMIDAZO[1,2-B]PYRIDAZINE-BASED COMPOUNDS, COMPOSITIONS COMPRISING THEM, AND USES THEREOF | LEXICON PHARMACEUTICALS INC (US) | 2018-05-02 | — | — | EP | disclosed |