⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20119656 | 1.00 | — | — | |
| SCHEMBL18194628 | 1.00 | — | — | |
| SCHEMBL24982524 | 0.80 | — | — | |
| SCHEMBL12918668 | 0.77 | — | — | |
| SCHEMBL12654740 | 0.77 | — | — | |
| SCHEMBL8600311 | 0.76 | — | — | |
| SCHEMBL8108922 | 0.76 | — | — | |
| SCHEMBL8079810 | 0.76 | — | — | |
| SCHEMBL9488886 | 0.76 | — | — | |
| SCHEMBL9598856 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10676475-B2 | Compounds for improving mRNA splicing | THE GENERAL HOSPITAL CORPORATION (US) | 2020-06-09 | — | — | US | disclosed |
| US-20180118748-A1 | Compounds for Improving mRNA Splicing | THE GENERAL HOSPITAL CORPORATION | 2018-05-03 | — | — | US | disclosed |