SCHEMBL2012070

SCHEMBL2012070

CCNc1ccc2c(c1)S(=O)(=O)NC2=O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 16/20 0.56
CA9 Q16790 16/20 0.56
CA2 P00918 14/20 0.56
CA7 P43166 9/20 0.56
CA1 P00915 7/20 0.51
XDH P47989 1/20 0.48
GLO1 Q04760 1/20 0.48
KDM4E B2RXH2 1/20 0.46
USP2 O75604 1/20 0.46
LMNA P02545 1/20 0.46
BCHE P06276 1/20 0.46
CA4 P22748 1/20 0.46
CA6 P23280 1/20 0.46
CA5A P35218 1/20 0.46
KMT2A Q03164 1/20 0.46
CA14 Q9ULX7 1/20 0.46
CA5B Q9Y2D0 1/20 0.46
CHEK1 O14757 1/20 0.45
DAPK3 O43293 1/20 0.45
MAP4K4 O95819 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13931190 0.78 CA12 (0.81) CA12CA9CA2CA7CA1
SCHEMBL7280720 0.77 CA12 (0.54) CA12CA9CA2CA7CA1
SCHEMBL28755346 0.76 CA12 (0.56) CA12CA9CA2CA7CA1
SCHEMBL20878400 0.76 CA12 (0.68) CA12CA9CA2CA7CA1
SCHEMBL1249735 0.73 CA12 (0.62) CA12CA9CA2CA7CA1
SCHEMBL29349483 0.73 CA12 (0.62) CA12CA9CA2CA7CA1
SCHEMBL16892302 0.72 CA12 (0.53) CA12CA9CA2CA7CA1
SCHEMBL11681555 0.72 CA12 (0.53) CA12CA9CA2CA7CA1
SCHEMBL9690124 0.72 CA12 (0.68) CA12CA9CA2CA7CA1
SCHEMBL6341593 0.71 KDM4E (0.58) KDM4EKMT2ACHEK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2513229-B1 DISPERSE AZO DYES, A PROCESS FOR THE PREPARATION THEREOF AND THE USE THEREOF HUNTSMAN ADV MAT SWITZERLAND (CH) 2014-04-23 EP disclosed
EP-2513229-A1 DISPERSE AZO DYES, A PROCESS FOR THE PREPARATION THEREOF AND THE USE THEREOF Huntsman Advanced Materials (Switzerland) GmbH (CH) 2012-10-24 EP disclosed
WO-2011072966-A1 DISPERSE AZO DYES, A PROCESS FOR THE PREPARATION THEREOF AND THE USE THEREOF HUNSTSMAN ADVANCED MATERIALS (SWITZERLAND) GMBH (CH) 2011-06-23 WO disclosed