Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PADI4 | Q9UM07 | 20/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18969398 | 1.00 | PADI4 (0.71) | PADI4 | |
| SCHEMBL18976214 | 1.00 | PADI4 (0.71) | PADI4 | |
| SCHEMBL18956488 | 1.00 | PADI4 (0.71) | PADI4 | |
| SCHEMBL23865690 | 0.94 | PADI4 (0.62) | PADI4 | |
| SCHEMBL18969466 | 0.94 | PADI4 (0.70) | PADI4 | |
| SCHEMBL18969357 | 0.90 | PADI4 (0.76) | PADI4 | |
| SCHEMBL18969406 | 0.90 | PADI4 (0.76) | PADI4 | |
| SCHEMBL18969356 | 0.90 | PADI4 (0.76) | PADI4 | |
| SCHEMBL20121069 | 0.90 | PADI4 (0.76) | PADI4 | |
| SCHEMBL18969578 | 0.90 | PADI4 (0.78) | PADI4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9963448-B2 | Bicyclic inhibitors of PAD4 | PADLOCK THERAPEUTICS, INC. (US) | 2018-05-08 | — | — | US | disclosed |
| US-9963448-B2 | Bicyclic inhibitors of PAD4 | PADLOCK THERAPEUTICS, INC. (US) | 2018-05-08 | — | — | US | disclosed |