Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21166520 | 0.71 | — | — | |
| SCHEMBL19787587 | 0.66 | — | — | |
| SCHEMBL23617252 | 0.65 | — | — | |
| SCHEMBL23159613 | 0.65 | — | — | |
| SCHEMBL19646921 | 0.64 | — | — | |
| SCHEMBL21455906 | 0.63 | TDP1 (0.36) | TDP1 | |
| SCHEMBL23600526 | 0.62 | — | — | |
| SCHEMBL12252072 | 0.62 | — | — | |
| SCHEMBL23601272 | 0.62 | — | — | |
| SCHEMBL20814502 | 0.62 | TDP1 (0.35) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9963448-B2 | Bicyclic inhibitors of PAD4 | PADLOCK THERAPEUTICS, INC. (US) | 2018-05-08 | — | — | US | disclosed |