⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23269829 | 0.82 | GGPS1 (0.33) | — | |
| SCHEMBL29616815 | 0.78 | KMT2A (0.60) | — | |
| SCHEMBL27008003 | 0.78 | KMT2A (0.60) | — | |
| SCHEMBL1698052 | 0.78 | KMT2A (0.41) | — | |
| SCHEMBL4277832 | 0.78 | — | — | |
| SCHEMBL15416747 | 0.77 | — | — | |
| SCHEMBL31226173 | 0.77 | — | — | |
| SCHEMBL4653602 | 0.77 | KMT2A (0.64) | — | |
| SCHEMBL28674475 | 0.77 | KMT2A (0.64) | — | |
| SCHEMBL8623650 | 0.77 | KMT2A (0.64) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10738021-B2 | Preparation of TMTHF | NITTO BELGIUM B.V. (BE) | 2020-08-11 | — | — | US | claimed |
| EP-3500561-B1 | PREPARATION OF TMTHF | NITTO BELGIUM NV (BE) | 2020-06-17 | — | — | EP | claimed |
| US-20190284150-A1 | PREPARATION OF TMTHF | NITTO BELGIUM B.V. (BE) | 2019-09-19 | — | — | US | claimed |
| EP-3500561-A1 | PREPARATION OF TMTHF | Nitto Belgium NV (BE) | 2019-06-26 | — | — | EP | claimed |
| WO-2018033635-A1 | PREPARATION OF TMTHF | NITTO BELGIUM NV (BE) | 2018-02-22 | — | — | WO | claimed |
| US-10738021-B2 | Preparation of TMTHF | NITTO BELGIUM B.V. (BE) | 2020-08-11 | — | — | US | disclosed |
| US-10738021-B2 | Preparation of TMTHF | NITTO BELGIUM B.V. (BE) | 2020-08-11 | — | — | US | disclosed |
| US-10738021-B2 | Preparation of TMTHF | NITTO BELGIUM B.V. (BE) | 2020-08-11 | — | — | US | disclosed |
| EP-3500561-B1 | PREPARATION OF TMTHF | NITTO BELGIUM NV (BE) | 2020-06-17 | — | — | EP | disclosed |
| US-20190284150-A1 | PREPARATION OF TMTHF | NITTO BELGIUM B.V. (BE) | 2019-09-19 | — | — | US | disclosed |
| US-20190284150-A1 | PREPARATION OF TMTHF | NITTO BELGIUM B.V. (BE) | 2019-09-19 | — | — | US | disclosed |
| US-20190284150-A1 | PREPARATION OF TMTHF | NITTO BELGIUM B.V. (BE) | 2019-09-19 | — | — | US | disclosed |
| EP-3500561-A1 | PREPARATION OF TMTHF | Nitto Belgium NV (BE) | 2019-06-26 | — | — | EP | disclosed |
| EP-3500561-A1 | PREPARATION OF TMTHF | Nitto Belgium NV (BE) | 2019-06-26 | — | — | EP | disclosed |
| CN-109790134-A | The preparation of TMTHF | 日东比利时公司 | 2019-05-21 | — | — | CN | disclosed |
| CN-109790134-A | The preparation of TMTHF | 日东比利时公司 | 2019-05-21 | — | — | CN | disclosed |
| WO-2018033635-A1 | PREPARATION OF TMTHF | NITTO BELGIUM NV (BE) | 2018-02-22 | — | — | WO | disclosed |
| WO-2018033635-A1 | PREPARATION OF TMTHF | NITTO BELGIUM NV (BE) | 2018-02-22 | — | — | WO | disclosed |
| EP-2336340-A1 | Method for producing an alkene comprising the step of converting an alcohol by an enzymatic dehydration step | Marliere, Philippe (FR) | 2011-06-22 | — | — | EP | disclosed |
| EP-2336341-A1 | Method for producing an alkene comprising the step of converting an alcohol by an enzymatic dehydration step | Marliere, Philippe (FR) | 2011-06-22 | — | — | EP | disclosed |