Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 9/20 | 0.44 |
| ▸ | CTSS | P25774 | 4/20 | 0.44 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.39 |
| ▸ | TGM2 | P21980 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16504745 | 1.00 | MEN1 (0.46) | MEN1KMT2AGAAALDH1A1TSHR | |
| SCHEMBL16504877 | 1.00 | MEN1 (0.46) | MEN1KMT2AGAAALDH1A1TSHR | |
| SCHEMBL21372526 | 1.00 | MEN1 (0.46) | MEN1KMT2AGAAALDH1A1TSHR | |
| SCHEMBL16504878 | 1.00 | MEN1 (0.46) | MEN1KMT2AGAAALDH1A1TSHR | |
| SCHEMBL15537106 | 1.00 | MEN1 (0.46) | MEN1KMT2AGAAALDH1A1TSHR | |
| SCHEMBL5632003 | 0.96 | MEN1 (0.50) | MEN1KMT2AGAAALDH1A1TSHR | |
| SCHEMBL22473734 | 0.96 | MEN1 (0.50) | MEN1KMT2AGAAALDH1A1TSHR | |
| SCHEMBL8353739 | 0.96 | MEN1 (0.50) | MEN1KMT2AGAAALDH1A1TSHR | |
| SCHEMBL15124799 | 0.96 | MEN1 (0.50) | MEN1KMT2AGAAALDH1A1TSHR | |
| SCHEMBL3439703 | 0.96 | MEN1 (0.50) | MEN1KMT2AGAAALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3035923-B1 | DITHIOL MUCOLYTIC AGENTS | PARION SCIENCES INC (US) | 2019-09-25 | — | — | EP | disclosed |
| US-9963427-B2 | Dithiol mucolytic agents | PARION SCIENCES, INC. (US) | 2018-05-08 | — | — | US | disclosed |