SCHEMBL20122344

SCHEMBL20122344

CC(C)n1cnc(C(C)(C)c2cccs2)c1

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KDM5A P29375 1/20 0.37
CNR1 P21554 3/20 0.35
CNR2 P34972 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9876139 0.71 KDM5A (0.35) KDM5A
SCHEMBL13706022 0.69 CNR1 (0.47) CNR1CNR2
SCHEMBL14417138 0.69 KDM5A (0.36) KDM5A
SCHEMBL16843172 0.67 GCK (0.35) KDM5A
SCHEMBL27922449 0.66 KDM5A (0.32) KDM5A
SCHEMBL307221 0.64
SCHEMBL25689901 0.62 SMN1; SMN2 (0.41) CNR1CNR2
SCHEMBL25457183 0.62 CNR1 (0.42) CNR1CNR2
SCHEMBL14777822 0.61
SCHEMBL27564815 0.61 CNR1 (0.49) CNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9963455-B2 Pyrazolo[1,5-a]pyrimidines as antiviral compounds CUROVIR AB (SE) 2018-05-08 US disclosed