Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.33 |
| ▸ | PPARA | Q07869 | 7/20 | 0.33 |
| ▸ | PPARD | Q03181 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20122408 | 0.95 | PPARG (0.33) | PPARGPPARAPPARDCYP1A2CYP2C9 | |
| SCHEMBL20122447 | 0.93 | — | — | |
| SCHEMBL20122509 | 0.88 | — | — | |
| SCHEMBL20122513 | 0.88 | — | — | |
| SCHEMBL20122589 | 0.88 | CYP1A2 (0.32) | CYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL20122505 | 0.86 | — | — | |
| SCHEMBL20122503 | 0.86 | — | — | |
| SCHEMBL20122520 | 0.86 | — | — | |
| SCHEMBL20122462 | 0.84 | PPARA (0.46) | PPARGPPARAPPARDCYP1A2CYP2C9 | |
| SCHEMBL20122590 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9963428-B1 | Bucillamine prodrugs, pharmaceutical compositions thereof, and methods of use | Nguyen, Mark Quang (US) | 2018-05-08 | — | — | US | disclosed |