Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.33 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.33 |
| ▸ | ITGAL | P20701 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20122649 | 0.87 | KMT2A (0.33) | KMT2AITGB2ICAM1ITGAL | |
| SCHEMBL16454357 | 0.86 | KMT2A (0.36) | KMT2AITGB2ICAM1ITGALUSP2 | |
| SCHEMBL19413057 | 0.74 | AOC3 (0.34) | — | |
| SCHEMBL19068905 | 0.72 | CYP1A2 (0.35) | ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL15114916 | 0.72 | KMT2A (0.39) | KMT2AITGB2ICAM1ITGALUSP2 | |
| SCHEMBL20122655 | 0.71 | CYP1A2 (0.37) | ALDH1A1TP53CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL16091182 | 0.71 | KMT2A (0.38) | KMT2AITGB2ICAM1ITGALUSP2 | |
| SCHEMBL22065025 | 0.71 | NPC1 (0.30) | — | |
| SCHEMBL16477266 | 0.69 | KMT2A (0.51) | KMT2AALDH1A1TP53CYP1A2CYP3A4 | |
| SCHEMBL21091671 | 0.69 | CNR2 (0.34) | ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9963445-B2 | Chemical compounds | SYNGENTA LIMITED (GB) | 2018-05-08 | — | — | US | disclosed |