Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | MIF | P14174 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14601911 | 0.83 | CA1 (0.48) | CA1CA2SMN1; SMN2ZDHHC7MGAM | |
| SCHEMBL16626822 | 0.83 | CA1 (0.48) | CA1CA2SMN1; SMN2ZDHHC7MGAM | |
| SCHEMBL8016992 | 0.77 | CA1 (0.41) | CA1CA2SMN1; SMN2ZDHHC7MGAM | |
| SCHEMBL14195390 | 0.77 | CA1 (0.45) | CA1CA2SMN1; SMN2ZDHHC7CA14 | |
| SCHEMBL2864267 | 0.77 | SMN1; SMN2 (0.48) | CA1CA2SMN1; SMN2ZDHHC7MGAM | |
| SCHEMBL13443752 | 0.76 | SMN1; SMN2 (0.46) | CA1CA2SMN1; SMN2ZDHHC7MGAM | |
| SCHEMBL13443753 | 0.76 | SMN1; SMN2 (0.46) | CA1CA2SMN1; SMN2ZDHHC7MGAM | |
| SCHEMBL7433060 | 0.76 | SMN1; SMN2 (0.46) | CA1CA2SMN1; SMN2ZDHHC7MGAM | |
| SCHEMBL4753760 | 0.74 | CA1 (0.42) | CA1CA2SMN1; SMN2ZDHHC7MGAM | |
| SCHEMBL15015843 | 0.74 | CA1 (0.42) | CA1CA2SMN1; SMN2ZDHHC7MGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9963445-B2 | Chemical compounds | SYNGENTA LIMITED (GB) | 2018-05-08 | — | — | US | disclosed |