Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 4/20 | 0.49 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | CDC25A | P30304 | 1/20 | 0.32 |
| ▸ | CDC25B | P30305 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13049470 | 0.76 | TDP1 (0.55) | APEX1CDC25ACDC25BTDP1 | |
| SCHEMBL13079426 | 0.76 | TDP1 (0.55) | APEX1CDC25ACDC25BTDP1 | |
| SCHEMBL13049463 | 0.73 | APEX1 (0.49) | APEX1TDP1 | |
| SCHEMBL20123268 | 0.70 | BCHE (0.36) | ACHEBCHE | |
| SCHEMBL13049441 | 0.69 | APEX1 (1.00) | APEX1CDC25ACDC25B | |
| SCHEMBL3802683 | 0.67 | APEX1 (0.60) | APEX1CDC25ACDC25B | |
| SCHEMBL13326329 | 0.66 | KMT2A (0.30) | — | |
| SCHEMBL15985021 | 0.66 | EPHX1 (0.38) | TDP1 | |
| SCHEMBL5569598 | 0.63 | TDP1 (0.42) | APEX1ACHETDP1 | |
| SCHEMBL13894616 | 0.62 | APEX1 (0.84) | APEX1CDC25ACDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2203161-B1 | QUINONE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | UNIV INDIANA RES & TECH CORP (US) | 2018-05-09 | — | — | EP | disclosed |