SCHEMBL20123932

SCHEMBL20123932

CC/C(C)=C/C=C\c1c(C)ccn2c(C)c(CCc3ccc4cc(C)cnc4n3)nc12

nearest known ligand 0.45

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21323851 0.89 PDE10A (0.46) PDE10A
SCHEMBL20123985 0.78 PDE10A (0.48) PDE10A
SCHEMBL12067664 0.75 PDE10A (0.52) PDE10A
SCHEMBL20123959 0.72 PDE10A (0.43) PDE10A
SCHEMBL15033409 0.72 PDE10A (0.78) PDE10A
Hydrochloric Acid SCHEMBL7516757 0.72 PDE10A (0.77) PDE10A
SCHEMBL7513931 0.64 PDE10A (0.78) PDE10A
SCHEMBL12067659 0.62 PDE10A (1.00) PDE10A
Hydrochloric Acid SCHEMBL15024106 0.61 PDE10A (0.98) PDE10A
SCHEMBL7510984 0.61 PDE10A (0.69) PDE10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3318561-B1 HETEROARYL COMPOUNDS AND METHODS OF USE THEREOF SUNOVION PHARMACEUTICALS INC (US) 2021-12-22 EP disclosed
EP-3318561-A1 HETEROARYL COMPOUNDS AND METHODS OF USE THEREOF Sunovion Pharmaceuticals Inc. (US) 2018-05-09 EP disclosed