Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.77 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.72 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.72 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.60 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.60 |
| ▸ | PPARG | P37231 | 2/20 | 0.58 |
| ▸ | BID | P55957 | 3/20 | 0.54 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.54 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.54 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.54 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.54 |
| ▸ | EP300 | Q09472 | 1/20 | 0.54 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.54 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.54 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.54 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.54 |
| ▸ | PLK1 | P53350 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | THRA | P10827 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2945568 | 1.00 | PPARA (0.77) | PPARAHDAC1HDAC6ALOX5PTGS2 | |
| SCHEMBL4142799 | 0.92 | PPARA (0.67) | PPARAHDAC1HDAC6ALOX5PTGS2 | |
| SCHEMBL4142804 | 0.92 | PPARA (0.67) | PPARAHDAC1HDAC6ALOX5PTGS2 | |
| SCHEMBL10829173 | 0.88 | PPARA (0.61) | PPARAHDAC1HDAC6ALOX5PTGS2 | |
| SCHEMBL2940835 | 0.87 | PPARA (1.00) | PPARAHDAC1HDAC6ALOX5PTGS2 | |
| SCHEMBL18030237 | 0.87 | PPARA (1.00) | PPARAHDAC1HDAC6ALOX5PTGS2 | |
| SCHEMBL2946573 | 0.86 | PPARA (0.77) | PPARAHDAC1HDAC6ALOX5PTGS2 | |
| SCHEMBL4142111 | 0.85 | HDAC1 (0.61) | PPARAHDAC1HDAC6ALOX5PTGS2 | |
| SCHEMBL4142107 | 0.85 | HDAC1 (0.61) | PPARAHDAC1HDAC6ALOX5PTGS2 | |
| SCHEMBL29044856 | 0.84 | PPARA (0.58) | PPARAHDAC1HDAC6ALOX5PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3099654-B1 | SYNTHETIC METHOD | UNIV COURT UNIV ST ANDREWS (GB) | 2018-05-09 | — | — | EP | disclosed |