Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 5/20 | 0.44 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.44 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.44 |
| ▸ | EGFR | P00533 | 5/20 | 0.42 |
| ▸ | INSR | P06213 | 1/20 | 0.42 |
| ▸ | AXL | P30530 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 2/20 | 0.41 |
| ▸ | CSF1R | P07333 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9943627 | 0.93 | NTRK1 (0.47) | NTRK1KDREPHA2EPHB4EGFR | |
| SCHEMBL9942806 | 0.85 | HRH3 (0.45) | NTRK1KDREPHA2EPHB4AXL | |
| SCHEMBL22137743 | 0.83 | NTRK1 (0.51) | NTRK1KDREPHA2EPHB4TSHR | |
| SCHEMBL29498285 | 0.81 | NTRK1 (0.49) | NTRK1KDREGFRINSR | |
| SCHEMBL17443160 | 0.81 | NTRK1 (0.49) | NTRK1KDREGFRINSR | |
| SCHEMBL24218717 | 0.79 | HTR2A (0.41) | NTRK1KDREPHA2EPHB4INSR | |
| SCHEMBL9937979 | 0.79 | NTRK1 (0.42) | NTRK1KDREPHA2EPHB4BACE1 | |
| SCHEMBL9972390 | 0.78 | KDR (0.56) | NTRK1KDREPHA2EPHB4EGFR | |
| SCHEMBL17434796 | 0.77 | ABL1 (0.52) | NTRK1TSHRMAPK14 | |
| SCHEMBL17434804 | 0.75 | NTRK1 (0.47) | NTRK1EGFRBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651416-B1 | COMPOUNDS USEFUL FOR TREATING AIDS | ABIVAX (FR) | 2018-05-09 | — | — | EP | disclosed |