SCHEMBL20124719

SCHEMBL20124719

CC(=O)N(Cc1ccc(Cc2cc(C3CC(O)CC(CO)O3)ccc2Cl)cc1)C1CC1

nearest known ligand 0.46

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SLC5A2 P31639 19/20 0.46
SLC5A1 P13866 14/20 0.41
DRD2 P14416 1/20 0.39
DRD1 P21728 1/20 0.39
DRD5 P21918 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20343943 0.82 SLC5A2 (0.57) SLC5A2SLC5A1
SCHEMBL12167159 0.81 SLC5A2 (0.53) SLC5A2SLC5A1
SCHEMBL19415587 0.81 SLC5A2 (0.56) SLC5A2SLC5A1
SCHEMBL15368221 0.81 SLC5A2 (0.56) SLC5A2SLC5A1
SCHEMBL10212405 0.81 SLC5A2 (0.56) SLC5A2SLC5A1
SCHEMBL19494583 0.81 SLC5A2 (0.56) SLC5A2SLC5A1
SCHEMBL12167415 0.80 SLC5A2 (0.46) SLC5A2SLC5A1
SCHEMBL12167132 0.80 SLC5A2 (0.55) SLC5A2SLC5A1
SCHEMBL12167281 0.80 SLC5A2 (0.52) SLC5A2SLC5A1
SCHEMBL27368163 0.80 SLC5A2 (0.52) SLC5A2SLC5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3318562-A2 BENZYLBENZENE DERIVATIVES AND METHODS OF USE Theracos Sub, LLC (US) 2018-05-09 EP disclosed