Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.49 |
| ▸ | CTPS1 | P17812 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29749170 | 1.00 | MAPT (0.50) | MAPTALDH1A1MEN1KMT2AFFAR2 | |
| SCHEMBL30776020 | 0.85 | MAPT (0.49) | MAPTALDH1A1MEN1KMT2ACTPS1 | |
| SCHEMBL2976966 | 0.83 | MAPT (0.73) | MAPTALDH1A1MEN1KMT2AFFAR2 | |
| SCHEMBL29748739 | 0.83 | MAPT (0.73) | MAPTALDH1A1MEN1KMT2AFFAR2 | |
| SCHEMBL15828726 | 0.83 | MAPT (0.59) | MAPTALDH1A1MEN1KMT2AFFAR2 | |
| SCHEMBL14754094 | 0.83 | MAPT (0.48) | MAPTALDH1A1MEN1KMT2ACTPS1 | |
| SCHEMBL28799327 | 0.82 | MAPT (0.55) | MAPTALDH1A1MEN1KMT2ACTPS1 | |
| SCHEMBL28799318 | 0.82 | KMT2A (0.56) | MAPTALDH1A1MEN1KMT2ACTPS1 | |
| SCHEMBL2039778 | 0.80 | TDP1 (0.74) | MAPTALDH1A1MEN1KMT2AFFAR2 | |
| SCHEMBL29788065 | 0.80 | TDP1 (0.74) | MAPTALDH1A1MEN1KMT2AFFAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108069937-B | Phenyl piperidine derivatives, methods of use and uses thereof | 广东东阳光药业有限公司 | 2022-07-26 | — | — | CN | disclosed |
| EP-3318557-A2 | QUINOLONE COMPOUND | Otsuka Pharmaceutical Co., Ltd. (JP) | 2018-05-09 | — | — | EP | disclosed |