Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL218977 | 0.88 | RECQL (0.60) | RECQLGAATDP1ALDH1A1CYP1A2 | |
| SCHEMBL6570943 | 0.83 | GAA (0.74) | RECQLGAATDP1ALDH1A1CYP1A2 | |
| SCHEMBL2570416 | 0.80 | GAA (0.59) | RECQLGAATDP1ALDH1A1CYP1A2 | |
| SCHEMBL3431305 | 0.79 | RECQL (0.69) | RECQLGAATDP1ALDH1A1CYP1A2 | |
| SCHEMBL24507059 | 0.78 | GAA (0.71) | RECQLGAATDP1ALDH1A1CYP1A2 | |
| SCHEMBL5550792 | 0.78 | GAA (0.66) | RECQLGAATDP1ALDH1A1CYP1A2 | |
| SCHEMBL14560518 | 0.77 | TDP1 (0.76) | RECQLGAATDP1ALDH1A1CYP1A2 | |
| SCHEMBL4853171 | 0.77 | GAA (0.65) | RECQLGAATDP1ALDH1A1CYP1A2 | |
| SCHEMBL17770699 | 0.77 | GAA (0.65) | RECQLGAATDP1ALDH1A1CYP1A2 | |
| SCHEMBL4851745 | 0.77 | RECQL (0.55) | RECQLGAATDP1ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4233834-A2 | ARYL-ANILINE AND HETEROARYL-ANILINE COMPOUNDS FOR TREATMENT OF BIRTHMARKS | NFlection Therapeutics, Inc. (US) | 2023-08-30 | — | — | EP | disclosed |
| EP-4233865-A2 | ARYL-ANILINE AND HETEROARYL-ANILINE COMPOUNDS FOR TREATMENT OF SKIN CANCERS | NFlection Therapeutics, Inc. (US) | 2023-08-30 | — | — | EP | disclosed |
| EP-3318567-A1 | TRICYCLIC COMPOUND HAVING SULFINYL OR SULFONYL | Shionogi & Co., Ltd (JP) | 2018-05-09 | — | — | EP | disclosed |