Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 10/20 | 0.84 |
| ▸ | KDM4A | O75164 | 3/20 | 0.84 |
| ▸ | KDM5B | Q9UGL1 | 14/20 | 0.67 |
| ▸ | KDM5A | P29375 | 13/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16150767 | 1.00 | KDM4C (0.84) | KDM4CKDM4AKDM5BKDM5A | |
| SCHEMBL16149653 | 0.92 | KDM4C (1.00) | KDM4CKDM4AKDM5BKDM5A | |
| SCHEMBL16149383 | 0.85 | KDM4C (0.64) | KDM4CKDM4AKDM5BKDM5A | |
| SCHEMBL16150732 | 0.84 | KDM5B (0.70) | KDM4CKDM4AKDM5BKDM5A | |
| SCHEMBL16150864 | 0.81 | KDM5A (1.00) | KDM4CKDM4AKDM5BKDM5A | |
| SCHEMBL16149493 | 0.80 | KDM5B (1.00) | KDM4CKDM4AKDM5BKDM5A | |
| SCHEMBL16157326 | 0.80 | KDM5A (1.00) | KDM4CKDM4AKDM5BKDM5A | |
| SCHEMBL17899546 | 0.78 | KDM5B (0.59) | KDM4CKDM4AKDM5BKDM5A | |
| SCHEMBL17899513 | 0.78 | KDM5B (0.59) | KDM4CKDM4AKDM5BKDM5A | |
| SCHEMBL16150955 | 0.78 | KDM4C (0.77) | KDM4CKDM4AKDM5BKDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968282-B1 | HISTONE DEMENTHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2018-05-09 | — | — | EP | disclosed |