Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 20/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15569686 | 0.85 | SYK (1.00) | SYK | |
| SCHEMBL14737008 | 0.84 | SYK (0.61) | SYK | |
| SCHEMBL22067905 | 0.84 | SYK (0.61) | SYK | |
| SCHEMBL19657319 | 0.84 | SYK (0.53) | SYK | |
| SCHEMBL1370213 | 0.83 | JAK3 (0.71) | SYK | |
| SCHEMBL22067901 | 0.82 | SYK (0.69) | SYK | |
| SCHEMBL12402577 | 0.80 | JAK3 (0.70) | SYK | |
| SCHEMBL15569961 | 0.80 | SYK (1.00) | SYK | |
| SCHEMBL15569819 | 0.80 | SYK (1.00) | SYK | |
| SCHEMBL15569530 | 0.79 | SYK (1.00) | SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3318565-A1 | PYRROLO[2,3-D]PYRIMIDINYL, PYRROLO[2,3-B]PYRAZINYL AND PYRROLO[2,3-D]PYRIDINYL ACRYLAMIDES | Pfizer Inc (US) | 2018-05-09 | — | — | EP | disclosed |