Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2204919 | 1.00 | MEN1 (0.33) | MEN1KMT2ATSHRMAPK1 | |
| SCHEMBL13082008 | 0.91 | TSHR (0.31) | TSHR | |
| SCHEMBL14802714 | 0.90 | — | — | |
| SCHEMBL4818972 | 0.87 | TSHR (0.31) | TSHR | |
| SCHEMBL19325220 | 0.86 | — | — | |
| SCHEMBL19325120 | 0.86 | TSHR (0.31) | TSHR | |
| SCHEMBL15044664 | 0.86 | — | — | |
| SCHEMBL20332237 | 0.86 | TSHR (0.31) | TSHR | |
| SCHEMBL14286687 | 0.86 | TSHR (0.31) | TSHR | |
| SCHEMBL15069874 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180127754-A1 | BIVALENT ANTISENSE OLIGONUCLEOTIDES | MIRRX THERAPEUTICS A/S (DK) | 2018-05-10 | — | — | US | disclosed |