Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 2/20 | 0.53 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2053851 | 1.00 | HCRTR1 (0.53) | HCRTR1HCRTR2EPHX2KMT2AMEN1 | |
| SCHEMBL2016308 | 0.93 | HCRTR1 (0.53) | HCRTR1HCRTR2EPHX2KMT2AMEN1 | |
| SCHEMBL2011495 | 0.93 | HCRTR1 (0.53) | HCRTR1HCRTR2EPHX2KMT2AMEN1 | |
| SCHEMBL13138976 | 0.87 | HCRTR1 (0.51) | HCRTR1HCRTR2EPHX2KMT2AMEN1 | |
| SCHEMBL13138952 | 0.87 | HCRTR1 (0.51) | HCRTR1HCRTR2EPHX2KMT2AMEN1 | |
| SCHEMBL2014120 | 0.85 | HCRTR1 (0.68) | HCRTR1HCRTR2HDAC3HDAC1 | |
| SCHEMBL2017845 | 0.85 | HCRTR1 (0.68) | HCRTR1HCRTR2HDAC3HDAC1 | |
| SCHEMBL13138970 | 0.84 | KMT2A (0.55) | HCRTR1HCRTR2EPHX2KMT2AMEN1 | |
| SCHEMBL13138994 | 0.84 | KMT2A (0.55) | HCRTR1HCRTR2EPHX2KMT2AMEN1 | |
| SCHEMBL2011137 | 0.83 | HCRTR1 (0.49) | HCRTR1HCRTR2EPHX2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011073316-A1 | 4-ARYL-BUTANE-1,3-DIAMIDES | NOVARTIS AG (CH) | 2011-06-23 | — | — | WO | disclosed |