Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20135688 | 0.83 | MAPT (0.38) | MAPTNPSR1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL20135150 | 0.81 | MAPT (0.36) | MAPTNPSR1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL20135375 | 0.75 | MAPT (0.41) | MAPTNPSR1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL12868073 | 0.75 | KMT2A (0.54) | MAPTSMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL20134842 | 0.74 | SMN1; SMN2 (0.49) | MAPTNPSR1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL20135239 | 0.72 | MAPT (0.39) | MAPTNPSR1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL20135236 | 0.72 | MAPT (0.39) | MAPTNPSR1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL838555 | 0.71 | CA12 (0.49) | MAPTSMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL20791702 | 0.71 | MAPT (0.38) | MAPTNPSR1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL20791683 | 0.70 | MAPT (0.39) | MAPTNPSR1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3321256-A1 | NOVEL IMIDE DERIVATIVES AND USE THEREOF AS MEDICINE | Mitsubishi Tanabe Pharma Corporation (JP) | 2018-05-16 | — | — | EP | disclosed |